回到榮民總醫院首頁

回到教學研究部首頁

榮民總醫院教學研究部網址

Human_molecular_genetics.jpg (9876 bytes)

 

TEL: +886-2-28712121 Ext.3265
E-mail: mychung@vghtpe.gov.tw
主持人:鍾明怡
1987 國立台灣大學 醫事技術學學士 鍾明怡老師
1990 美國明尼蘇達大學 臨床實驗科學碩士
1993 美國明尼蘇達大學 病理生物博士
1994 美國明尼蘇達大學 博士後研究分子遺傳 臨床細胞遺傳
1995-1997 台北榮民總醫院 病理檢驗部臨床細胞遺傳實驗室約聘技術師
1997-2005 台北榮民總醫院 教學研究部 副研究員
2002-2005 國立陽明大學 遺傳學研究所 兼任副教授
2005-- 國立陽明大學 生命科學系暨基因體科學研究所 副教授
2005-- 台北榮民總醫院教學研究部兼任副研究員
     
研究室夥伴    
契約醫檢師 許育華  
研究助理 林哲立、林照傑  
碩士班研究生 張仕翰、張純萍、莊毓婷  
 大學部學生 李孟儒、陳詩允  

實驗室合照

 

 

《研究興趣》

本研究室的研究興趣為利用分子生物技術了解基因在疾病中所扮演的角色。我們主要有兩個研究方向在進行:


1、新型小腦脊髓萎縮症基因之定位選殖。

2、色素性視網膜炎的分子遺傳學。

《近期研究著作》

1. Niu, D. M., Pan, C. C., Lin, C. Y., Hwang, B., and Chung, M. Y. (2002). Mosaic or chimera? Revisiting an old hypothesis about the cause of the 46,XX/46,XY hermaphrodite. J Pediatr 140, 732-735.

2. Chung, M. Y., Lu, Y. C., Cheng, N. C., and Soong, B. W. (2003). A novel autosomal dominant spinocerebellar ataxia (SCA22) linked to chromosome 1p21-q23. Brain 126, 1293-1299.

3. Chang, K. W., Lee, T. C., Yeh, W. I., Chung, M. Y., Liu, C. J., Chi, L. Y., and Lin, S. C. (2004). Polymorphism in heme oxygenase-1 (HO-1) promoter is related to the risk of oral squamous cell carcinoma occurring on male areca chewers. Br J Cancer 91, 1551-1555.

4. Chen, W. S., Chung, M. Y., Liu, J. H., Liu, J. M., and Lin, J. K. (2004). Impact of circulating free tumor cells in the peripheral blood of colorectal cancer patients during laparoscopic surgery. World J Surg 28, 552-557.

5. Lin, S. C., Chung, M. Y., Huang, J. W., Shieh, T. M., Liu, C. J., and Chang, K. W. (2004). Correlation between functional genotypes in the matrix metalloproteinases-1 promoter and risk of oral squamous cell carcinomas. J Oral Pathol Med 33, 323-326.

6. Lin, S. C., Lo, S. S., Liu, C. J., Chung, M. Y., Huang, J. W., and Chang, K. W. (2004). Functional genotype in matrix metalloproteinases-2 promoter is a risk factor for oral carcinogenesis. J Oral Pathol Med 33, 405-409.

7. Lin, S. C., Chang, M. F., Chung, M. Y., Chang, C. S., Kao, S. Y., Liu, C. J., and Chang, K. W. (2005). Frequent microsatellite alterations of chromosome locus 4q13.1 in oral squamous cell carcinomas. J Oral Pathol Med 34, 209-213.

8. Lin, C. C., Yang, W. C., Lin, S. J., Chen, T. W., Lee, W. S., Chang, C. F., Lee, P. C., Lee, S. D., Su, T. S., Fann, C. S., and Chung, M. Y. (2006). Length polymorphism in heme oxygenase-1 is associated with arteriovenous fistula patency in hemodialysis patients. Kidney Int 69, 165-172.

9. Chiang, C. H., Tang, Y. C., Lin, M. W., and Chung, M. Y. (2007). Association between the IL-4 promoter polymorphisms and asthma or severity of hyperresponsiveness in Taiwanese. Respirology 12, 42-48.

10. Huang, Y. C., Chen, M., Lin, M. W., Chung, M. Y., Chang, Y. H., Huang, W. J., Wu, T. T., Hsu, J. M., Yang, S., and Chen, Y. M. (2007). CYP19 TCT tri-nucleotide Del/Del genotype is a susceptibility marker for prostate cancer in a Taiwanese population. Urology 69, 996-1000.

11. Huang, Y. C., Lee, C. M., Chen, M., Chung, M. Y., Chang, Y. H., Huang, W. J., Ho, D. M., Pan, C. C., Wu, T. T., Yang, S., et al. (2007). Haplotypes, loss of heterozygosity, and expression levels of glycine N-methyltransferase in prostate cancer. Clin Cancer Res 13, 1412-1420.

12. Lin, C. H., Chung, M. Y., Chen, W. B., and Chien, C. H. (2007). Growth inhibitory effect of the human NIT2 gene and its allelic imbalance in cancers. Febs J 274, 2946-2956.

13. Lo, S. S., Lin, S. C., Wu, C. W., Chen, J. H., Yeh, W. I., Chung, M. Y., and Lui, W. Y. (2007). Heme oxygenase-1 gene promoter polymorphism is associated with risk of gastric adenocarcinoma and lymphovascular tumor invasion. Ann Surg Oncol 14, 2250-2256.

 

 

回到榮民總醫院首頁

回到教學研究部首頁

榮民總醫院教學研究部網址